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AdipoGen - 40B0041AAC500 - IL-33 (mouse) (rec.) (BULK) (Each (500 G))

Spacer AdipoGen - 40B0041AAC500 - IL-33 (mouse) (rec.) (BULK) (Each (500 G)) Spacer

Manufacturer: AdipoGen
Item #: 6167209
Mfr Part Number: 40B0041AAC500
MSRP: $4,183.11
Sale Price: Click for Price

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Interleukin-33 (IL-33; HF-NEV; IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released upon cell lysis. IL33 binds to and signals through ST2 (IL1R1) and its stimulation recruits MYD88, IRAK, IRAK4, and TRAF6, followed by phosphorylation of ERK1(MAPK3)/ERK2(MAPK1), p38(MAPK14), and JNK.

The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells, and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy & anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases, and sepsis.

This listing is for Each (500 G) Host E. coli Form Frozen liquid. Size 500 g Unit Each (500 G) Biological Activity Activates ST2-dependent NF-kappaB pathway. Clonality Protein Concentration Please inquire. Long Term Storage -20 C Molecular Weight ~18kDa Purity > 95% (SDS-PAGE) Sequence Mouse IL-33 (aa 109-266) is untagged.

Short Term Storage -20 C Species Crossreactivity Human , Mouse Specificity Binds to mouse and human ST2. Stability Stable for at least 6 months after receipt when stored at -20 C. Storage Buffer Frozen Contains PBS.. is your premier destination for business and facility products and services, including this AdipoGen - 40B0041AAC500 - IL-33 (mouse) (rec.) (BULK) (Each (500 G)). We usually ship via FedEx or UPS. Shipping & handling fees for non-freight shipments to all continental, contiguous USA addresses are customized in-cart for the delivery zip code.This AdipoGen - 40B0041AAC500 - IL-33 (mouse) (rec.) (BULK) (Each (500 G)) is currently on sale for $3,983.91, a discount of 5% off the list cost. California residents are subject to state and local Sales Tax. To request a phone system quote or to get info on the most suitable system for your operation, Click Here.

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