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Industrial And Scientific > Laboratory And Science > Life Science > Proteomics > Protein Detection > Protein Assays > Corning

Corning - 354165 - SYSTEM TUMOR INVASION 24WL. (Pack Of 1)

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Spacer Corning - 354165 - SYSTEM TUMOR INVASION 24WL. (Pack of 1) Spacer
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Manufacturer: Corning
Item #: 10387444
Mfr Part Number: 354165
MSRP: $466.19
Sale Price: Click for Price

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Corning BioCoat Tumor Invasion Systems provide cells with conditions that allow assessment of their invasive property in vitro. It consists of a Falcon FluoroBlok 24-Multiwell Insert Plate with an 8.0 micron pore size PET membrane that has been uniformly coated with Corning Matrigel Matrix.

This uniform layer of Corning Matrigel Matrix serves as a reconstituted basement membrane in vitro providing a true barrier to non-invasive cells while presenting an appropriate protein structure to study invasion. The coating process occludes the pores of the membrane, blocking non-invasive cells from migrating through the membrane.

In contrast, invasive cells (malignant and non-malignant cells) are able to detach themselves from and migrate through the coated membrane. Quantitation of cell invasion is achieved by either pre- or post-cell invasion labeling with a fluorescent dye such as DiIC12(3) or calcein AM, respectively, and measuring the fluorescence of invading cells.

Includes a 24- or 96-Multiwell insert plate containing an 8.0 m pore size FluoroBlok polyethylene terephthalate membrane coated with Corning Matrigel Matrix; the matrix provides a true barrier to noninvasive cells while presenting an appropriate protein structure for invading cells to penetrate and pass through the FluoroBlok membrane.

Key Features Provides an environment that allows for the assessment of the invasive potential of cells in vitro Ideal for studies of the metastatic potential of tumor cells and the inhibition of invasion by antineoplastic drugs Saves time and labor when screening for prospective antimetastatic compounds Eliminates tedious manual cell scraping and counting Each lot is tested for the ability to allow invasion of HT-1080 cells (an invasive human fibrosarcoma cell line) and to exclude invasion of 3T3 cells (a noninvasive fibroblast cell line) Automation compatible 1 insert plate w/ one 24-well plate & lid This listing is for Case of 1.





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