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Industrial And Scientific > Laboratory And Science > Life Science > Genomics > Signal Transduction Cell Based Assays > EMD Millipore

EMD Millipore - 05-23-3800-1MG - Endothelin 1, Human And Porcine - CAS 117399-94-7 - Calbiochem

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Spacer EMD Millipore - 05-23-3800-1MG - Endothelin 1, Human and Porcine - CAS 117399-94-7 - Calbiochem Spacer
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Manufacturer: EMD Millipore
Item #: 6280200
Mfr Part Number: 05-23-3800-1MG
MSRP: $765.22
Sale Price: Click for Price

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Endothelin 1, Human and Porcine, CAS 117399-94-7, is a 21-amino acid polypeptide with potent vasoconstrictive action. Activates phospholipase C in fibroblasts expressing ETA receptors. This listing is for 1 mg Plastic ampoule Overview A 21-amino acid polypeptide with potent vasoconstrictive action.

Produces convulsions, arterial hypertension, and metabolic activation of periventricular white and gray matter. Its effects are mediated via L-type Ca 2+ channels. Reported to activate phospholipase C in fibroblasts expressing ET A receptors. Brand Family Calbiochem Synonyms ET-1, CSCSSLMDKECVYFCHLDIIW References Cesari, M.

, et al. 1996. Am. Heart J. 132, 1236. Gresser, O., et al 1996. Biochem. Biophys. Res. Commun. 224, 169. Murata, S., et al. 1995. J. Pharmacol. Exp. Ther. 274, 1524. Hexum, T.D., et al. 1990. Biochem. Biophys. Res. Commun. 167, 294. Itoh, Y., et al. 1988. FEBS Lett. 231, 440. Yanagisawa, M.

, et al. 1988. Nature 332, 411. CAS number 117399-94-7 ATP Competitive N Form White to off-white solid Formulation Supplied as an acetate salt. Hill Formula CHNOS Chemical formula CHNOS Reversible N Sold on the basis of peptide content Y Primary Target Potent vasoconstrictive action Purity 96% by HPLC Cell permeable N Peptide Content Y Peptide Sequence H-Cys -Ser-Cys -Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys -Val-Tyr-Phe-Cys -His-Leu-Asp-Ile-Ile-Trp-OH (disulfide bonds: 1 15; 3 11) Ship Code Ambient Temperature Only Toxicity Standard Handling Storage -20 C Protect from Moisture Protect from moisture Do not freeze Ok to freeze Special Instructions Following reconstitution, aliquot and freeze (-20 C).

Stock solutions are stable for up to 2 weeks at -20 C..



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